photo of Lenore Goldfarb

recurrent miscarriage
IMMUNE TESTING

GENETICS

RECURRENT MISCARRIAGE:
CAUSES, EVALUATION,
AND TREATMENT

ADDITIONAL READING

Recurrent miscarriage is a complex and controversial issue but it can be successfully treated step by step. First, if you can get pregnant naturally you are halfway there. If you cannot get pregnant without assisted reproductive technology you must attack your problem on two fronts. You must see the issue as having
  1. a physical component and
  2. an immune component.
Physical complications of pregnancy can be overcome through the use of a variety of assisted reproductive techniques.


Immune Testing
 
Genetics

A Word About Genetics

Instructions for Preserving Fetal/Placental Tissue & Genetic Testing

Cytogenetic profiles

Other Resources

The Alan E. Beer Center for Reproductive Immunology & Genetics
The Alan E. Beer Center for Reproductive Immunology & Genetics researches and treats couples who experience recurrent miscarriages, multiple pregnancy losses or repeated in vitro fertilization failures. They offer comprehensive testing and boast an 85% success rate in achieving successful pregnancies for these couples.

Inflammatory Effector Mechanisms Laboratory, Dr. Jane Salmon
Dr. Salmon is Professor of Medicine and Professor of Obstetrics and Gynecology at Weill Medical College and the Collette Kean Research Professor at Hospital for Special Surgery.

Dr. Mary Stephenson
Dr. Stephenson is an internationally renown expert in the treatment of recurrent miscarriage. She is the Director of the Recurrent Pregnancy Loss Program at University of Chicago.

SHER Institutes for Reproductive Medicine
Specializing in the diagnosis and treatment of Immunologic Implantation Failure.

Life Quest
The START Clinic has a new name: Life Quest IVF www.lifequestivf.com. Dr. Carl Laskin heads the T.E.R.M. program. Using innovative and often experimental therapies, the T.E.R.M. program (Treatment and Evaluation of Recurrent Miscarriage) takes a caring and detailed approach to the investigation and management of recurrent miscarriage. It offers patients unique medical therapy for this complex problem, in a supportive environment. T.E.R.M. is the largest program in Canada devoted to studying and treating unexplained and recurrent miscarriage.

Life Quest IVF
Telephone 416-506-0804
655 Bay Street, 18th Floor,
Toronto, Ontario,
M5G 2K4.


Comprehensive Recurrent Miscarriage Information
Recurrent Miscarriage: causes, evaluation, and treatment
Medscape Women's Health 1998 May;3(3):2 (ISSN: 1521-2076)

Introduction

Relationship to Spontaneous Abortion

Role of Chromosomal Anomalies in Recurrent Spontaneous Abortion

Relevance of Family History

Cytogenetic Studies

Genetic Counseling

Blood Coagulation Protein or Platelet Defects

Hemorrhagic Defects

Thrombotic Defects

Anatomic Abnormalities

Endocrine Abnormalities

References

Tables


Additional Reading
 

Web Sites

Links to Web Sites with More Information



2005

Gene Tied to Late Miscarriage
By Carolyn Abraham - Globe and Mail

2004

Scientists on Trail of Miscarriage Mystery
By Luma Muhtadie - Globe and Mail

2001

Pregnancy outcome in recurrent spontaneous abortion associated with antiphospholipid antibodies: a comparative study of intravenous immunoglobulin versus prednisone plus low-dose aspirin
Am J Reprod Immunol 2001 Mar;45(3):174-9 (ISSN: 1046-7408)

2000
Successful uterine steroid therapy in a case with a history of ten miscarriages
Am J Reprod Immunol 2000 Oct;44(4):253-5 (ISSN: 1046-7408)

Is the paternal mononuclear cells' immunization a successful treatment for recurrent spontaneous abortion?
Am J Reprod Immunol 2000 Sep;44(3):129-35 (ISSN: 1046-7408)

The use of intravenous immunoglobulin in sine causa or alloimmune recurrent spontaneous abortion (RSA)
Panminerva Med 2000 Sep;42(3):193-5 (ISSN: 0031-0808)

Pregnancy after four recurrent pregnancy losses: a case report
Ginekol Pol 2000 Jun;71(6):536-41 (ISSN: 0017-0011)

Effects of paternal lymphocyte immunization on peripheral Th1/Th2 balance and TCR V beta and V gamma repertoire usage of patients with recurrent spontaneous abortions
Am J Reprod Immunol 2000 Feb;43(2):107-15 (ISSN: 1046-7408)

1999
Pregnancy complications in women with recurrent miscarriage associated with antiphospholipid antibodies treated with low dose aspirin and heparin
Br J Obstet Gynaecol 1999 Feb;106(2):102-7 (ISSN: 0306-5456)

Is there a role for antithrombotic therapy in the prevention of pregnancy loss?
Haemostasis 1999 Dec;29 Suppl S1:112-20 (ISSN: 0301-0147)

Habitual abortions in 678 healthy patients: investigation and prevention
Hum Reprod 1999 Aug;14(8):2106-9 (ISSN: 0268-1161)

1998
Utilization of intravenous immunoglobulin therapy to treat recurrent pregnancy loss in the antiphospholipid syndrome: a review
Scand J Rheumatol Suppl 1998;107:97-102 (ISSN: 0301-3847)

Re-evaluation of immunomodulator treatments for recurrent abortions
Rev Med Brux 1998 Apr;19(2):69-72 (ISSN: 0035-3639)

Immunotherapy before and during pregnancy improves pregnancy outcome in women who suffer from recurrent abortion and did not benefit from immunotherapy before pregnancy
Am J Reprod Immunol 1998 Jan;39(1):12-5 (ISSN: 1046-7408)

1997
Recurrent fetal death and antiphospholipid antibody syndrome: A case report
Ginecol Obstet Mex 1997 Dec;65:523-8 (ISSN: 0300-9041)

Antiphospholipid antibodies, infertility and recurrent miscarriage
Curr Opin Obstet Gynecol 1997 Aug;9(4):279-82 (ISSN: 1040-872X)

Clinical and immunological condition of newborns of mothers treated for recurrent spontaneous abortions with paternal lymphocytes immunization
Eur J Obstet Gynecol Reprod Biol 1997 May;73(1):55-61 (ISSN: 0301-2115)

1995
Immunotherapy for recurrent spontaneous abortion.
Early Pregnancy 1995 Mar;1(1):13-26 (ISSN: 1354-4195)

If you value this service, kindly consider a donation to the Canadian Breastfeeding Foundation (registered charity) and earmark the donation for the Newman Breastfeeding Clinic and Institute and/or the Goldfarb Breastfeeding Program.

You can donate through their website, canadianbreastfeedingfoundation.org, or by mail to Canadian Breastfeeding Foundation, 5764 Monkland Ave, Suite 424, Montreal, Quebec, Canada, H4A 1E9.


Disclaimer: All material provided in asklenore.info is provided for educational purposes only. Consult your physician regarding the advisability of any opinions or recommendations with respect to your individual situation.